Eppendorf's market tradition centers on the Isemarkt, running every Tuesday and Friday since 1949 along Isestrasse beneath the elevated U3 line, alongside the smaller Marie-Jonas-Platz market held Tuesdays, Thursdays and Saturdays.

Eppendorf's best-known weekly market is the Isemarkt, which has run every Tuesday and Friday since 1949 along Isestrasse, set up directly beneath the elevated tracks of the U3 line. It draws roughly 6,000 shoppers on a typical market day and traces its roots to a 19th-century commodity-and-livestock market (Kram- und Viehmarkt) that had also doubled as a popular summer gathering with food stalls before the current market took its present form in the 1940s. A second, smaller market runs at Marie-Jonas-Platz on Tuesdays, Thursdays, and Saturdays; that site was a parking lot until the neighboring Karstadt department store closed in 2007, after which the space was converted into a market square selling fresh produce, fish, and prepared specialties with vendors offering cooking guidance. Both markets sell fresh regional produce, baked goods, flowers, and other grocery staples typical of a German Wochenmarkt, and together they cover most of Eppendorf's weekly market shopping across five days. Given the ambiguity in the source record, this rewrite covers both known Eppendorf markets rather than asserting a single one.